My 2 cents:
First, I would like to clearly distinguish between
(Confirmed) Human Sacrifice (as per Lust's words in that very same page you linked): An alchemist who has opened the Gates of Truth and came back. (And thus has clappy alchemy 'n stuff) and of whom the homunculi-tachi know about, of course (they don't know about neither Izumi nor, at least that we know, Jude).
Human Sacrifice Candidate: An alchemist who is considered intelligent/capable/smart/brave/whatever enough to, some day, open the Gates and enter the above mentioned group.
QUOTE(Ant @ May 7 2006, 08:22 PM) [snapback]391856[/snapback]
What is the nature of the "human sacrifices" the homunculi keep talking about?
We know that both Ed and Al are on the list, and we know that the homunculi want alchemists that have opened/seen the Gate
(as confirmed by Lust in Ch. 39).
Who else is on the list of "human sacrifices"? I recall Marcoh, Mustang, and I
think Scar too.
IIRC, only Marcoh and Mustang have been explicitly mentioned. I believe Armstrong is one too, or else I don't see a reason why he shouldn't have been killed (or tried to, at least

) like Hughes. Those 2 were the only ones in the group Bradley told to "shut up" that we hadn't been told if they were HSC or not.
And Scar, it's waaay the opposite. He's not a HSC, he's a nuisance precisely because he kills... eh... HSC Candidates

U so they want to wipe him out. ASAP.
BTW, Neph, you said they fear him, I disagree. He's a high-priority Problem, yes, cuz he's killing possible future HSC's, but they don't seem to really care that much (probably they think they can prepare enough HSC when they're needed anyway. It's just easier to use those that already are there

)
QUOTE(Ant @ May 7 2006, 08:22 PM) [snapback]391856[/snapback]
Why would State Alchemists that haven't seen the gate be on this list? In other words - are ALL state alchemists skilled enough to be considered valuable "human sacrifices"? Or are we to extrapolate that Marcoh/Mustang are either extremely skilled or have something in their past that makes them a valuable human sacrifice?
Definitely not all State Alchemists are HS. Rather the opposite, only a few... proof? They didn't care about Tucker's death (he was considered a third rate too) and they don't consider Kimbley to be good enough either. Plus Scar killed so many of them, and yet the only victim they seem to be (minorly) bothered about as of now is good ol' Basque Gran.
And why, or rather, at what point are they considered HSC? No friggin' idea. But we're talking about Father (almost-god-like alchemist) and the hommunculi (who live surrounded by alchemy themselves) here, I guess they know enough to be able to tell whether an alchemist "has what it takes" to open the Gates (and thus become a HSC) or not.

QUOTE(Ant @ May 7 2006, 08:22 PM) [snapback]391856[/snapback]
Also,
when Wrath says that he'll have Mustang open the gate, is this foreshadowing of Hawkeye's "captivity"; in other words, is he planning to use Hawkeye as leverage in order to make Mustang do his bidding, and "open the gate"?
Yes it was much probably a foreshadowing of Hawkeye's captiveness, because it was at that point when Wrath learnt about how really important is Riza to Roy. More precisely he said it because he had found a way to make Mustang open the Gates (through Riza somehow, indeed), because, hey, it's all good and nice to have them many a Human Sacrifice Candidate, but what they actually need is Human Sacrifices, not just Candidates, therefore, they need them to get the job done sooner or later.
Father was pleased to know Wrath had a plan for the Colonel (one more point for the bad guys) and therefore decided to trust the hommunculus and spare Roy's life.
To sum it all up, the situation as I see it:
- Confirmed Human Sacrifices:
Edward and Alphonse Elric.- Actual HS but only a Candidate for Father's people:
Izumi Curtis.- Actual HS but unknown whether the bad guys know about him or not:
Jude- Human Sacrifice Candidates per se:
Roy Mustang, Dr. Marcoh and Alex Louis Armstrong (this last one just my guess)
- Lost Human Sacrifice Candidate, at the hands of Scar:
Basque Gran- Not HSC:
Shou Tucker (low-rate alchemist who only -coldly- "cheated" his way to the State title)
and Kimbley (considered, but someone said he "doesn't have the guts").
And That's All Folks.
QUOTE(Ant @ May 7 2006, 08:22 PM) [snapback]391856[/snapback]
Having only read the Manga through once, and not having the time to read through it again as of now(...)
Be sure to reread it when you can! ( n_n)--b
QUOTE(MonsterEnvy @ May 8 2006, 02:30 AM) [snapback]392084[/snapback]
My opinions aren't based on too much information, but...
1. They only need five 'confirmed' human sacrifices. They need a hell of a lot of sacrifices, but why five confirmed? Because the array to transmute the philosopher's stone has five circles around the edges that were bloodstained. It's quite likely that those five are necessary, and then everyone else inside it is killed. So, a confirmed sacrifice would be stationed at different places around the perimieter of amestris, and be killed in the transmutation.
Hmmm? Now when did they say that in the manga? I mean, them bad guys needing 5 HS and each one of them needing to be in one of the Amestris' Big Circle spots. I don't recall reading such things in the manga... just as theories here. Correct me if I'm wrong, tho' >_<