Inspired by this:
NEON GENESIS EVANGELION: Pedophile finds God.
ELFEN LIED: College student molests mentally challenged girl.
INUYASHA: Elderly man with anger management issues develops romantic relationship with under-aged girl.
AZUMANGA DAIOH: Teenaged lesbians harassed by pedophile teacher.
RAHXEPHON: Teenager plays loud music; destroys world.
HARUHI SUZUMIYA: Mentally ill teenage girl molests classmates.
BLEACH: Revolutionary subverts oppressive government bureaucracy.
WOLF'S RAIN: Destruction of the world initiated by religious zealot.
FLCL: Young children assaulted, molested and impregnanted by insane illegal immigrant.
DENNOU COIL: Obsessive nerds terrorize each other, abuse their pets.
PARANOIA AGENT: Talented young athlete inspires people to change their lives.
SERIAL EXPERIMENTS LAIN: Young outcast becomes popular overnight.
EUREKA SEVEN: Fugitive pedophile abducts, assaults young runaway.
MONSTER: Charismatic young man harassed by stalker
EXCEL SAGA: Gaudily dressed schizophrenic finds gainful employment.
DEATH NOTE: Attractive young couple stalked by obsessed, socially awkward diabetics.
NOIR: Lesbian couple murders religious leader and her adopted daughter.
BLACK LAGOON: Bored businessman finds adventure in a tropical paradise.
LAST EXILE: Special needs child abducted by terrorist group.
and finally... FULLMETAL ALCHEMIST: Drag queen repeatedly abuses his handicapped half-brother.