The anime/manga I am looking needs to have a similar plot or story and tragic [the loss of someone precious]
GUN×SWORD (*pokes signature*)
Code Geass: Lelouch of the Rebellion
Le Chevalier d'Eon
Tsubasa RESERVoir CHRoNiCLE
Several of the animes/mangas people have suggested have either been to "girly" [need a man as the main character]
I agree; there are many anime/manga out there with female protagonists and are way awesome...and these include:
The Melancholy of Haruhi Suzumiya
R.O.D the TV and Read or Die
Ouran High School Host Club (Okay, this is shoujo, but it's very good shoujo)
But if you insist...
Fate/Stay Night (supporting lead is a girl though)
GUN×SWORD (supporting lead is a girl)
Le Chevalier d'Eon (supporting lead is a girl)
xxxHOLiC (slightly more focused on the male lead)
Tsubasa RESERVoir CHRoNiCLE (see above)
have been just to violent and the story seemed to fade as fast as the blood covered the screen.
I assure you, Blood+ may sound like all gore and no story, but it has an excellent plot, and is a lot less bloody than you may think. Same goes with everything I listed above. Also, try the manga versions of the anime.
Whether the anime or manga version of a fandom is better will be up to you.
You can always contact me for more info on the listed animanga (I can be a walking encyclopedia when I want to, because I tend to OBSESS over fandoms I love XD), thank you very much.